Topical Application of Recombinant Type VII Collagen Incorporates Into the Dermal–Epidermal Junction and Promotes Wound Closure

Patients with recessive dystrophic epidermolysis bullosa (RDEB) have incurable skin fragility, blistering, and skin wounds due to mutations in the gene that codes for type VII collagen (C7) that mediates dermal–epidermal adherence in human skin. In this study, we evaluated if topically applied human...

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Autors principals: Wang, Xinyi, Ghasri, Pedram, Amir, Mahsa, Hwang, Brian, Hou, Yingpin, Khilili, Michael, Lin, Andrew, Keene, Douglas, Uitto, Jouni, Woodley, David T, Chen, Mei
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704128/
https://ncbi.nlm.nih.gov/pubmed/23670575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.87
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