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Injection of Recombinant Human Type VII Collagen Corrects the Disease Phenotype in a Murine Model of Dystrophic Epidermolysis Bullosa

Patients with recessive dystrophic epidermolysis bullosa (RDEB) have incurable skin fragility, blistering, and scarring due to mutations in the gene that encodes for type VII collagen (C7) that mediates dermal–epidermal adherence in human skin. We showed previously that intradermal injection of reco...

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Detalhes bibliográficos
Main Authors: Remington, Jennifer, Wang, Xinyi, Hou, Yingpin, Zhou, Hui, Burnett, Julie, Muirhead, Trevor, Uitto, Jouni, Keene, Douglas R, Woodley, David T, Chen, Mei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834970/
https://ncbi.nlm.nih.gov/pubmed/19018253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.234
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