Injection of Recombinant Human Type VII Collagen Corrects the Disease Phenotype in a Murine Model of Dystrophic Epidermolysis Bullosa

Patients with recessive dystrophic epidermolysis bullosa (RDEB) have incurable skin fragility, blistering, and scarring due to mutations in the gene that encodes for type VII collagen (C7) that mediates dermal–epidermal adherence in human skin. We showed previously that intradermal injection of reco...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Remington, Jennifer, Wang, Xinyi, Hou, Yingpin, Zhou, Hui, Burnett, Julie, Muirhead, Trevor, Uitto, Jouni, Keene, Douglas R, Woodley, David T, Chen, Mei
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2008
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834970/
https://ncbi.nlm.nih.gov/pubmed/19018253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.234
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