Injection of Recombinant Human Type VII Collagen Corrects the Disease Phenotype in a Murine Model of Dystrophic Epidermolysis Bullosa

Patients with recessive dystrophic epidermolysis bullosa (RDEB) have incurable skin fragility, blistering, and scarring due to mutations in the gene that encodes for type VII collagen (C7) that mediates dermal–epidermal adherence in human skin. We showed previously that intradermal injection of reco...

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Bibliografiske detaljer
Main Authors: Remington, Jennifer, Wang, Xinyi, Hou, Yingpin, Zhou, Hui, Burnett, Julie, Muirhead, Trevor, Uitto, Jouni, Keene, Douglas R, Woodley, David T, Chen, Mei
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834970/
https://ncbi.nlm.nih.gov/pubmed/19018253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.234
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