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Muscarinic acetylcholine receptor activation blocks long-term potentiation at cerebellar parallel fiber–Purkinje cell synapses via cannabinoid signaling

Muscarinic acetylcholine receptors (mAChRs) are known to modulate synaptic plasticity in various brain areas. A signaling pathway triggered by mAChR activation is the production and release of endocannabinoids that bind to type 1 cannabinoid receptors (CB1R) located on synaptic terminals. Using whol...

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Detalles Bibliográficos
Main Authors: Rinaldo, Lorenzo, Hansel, Christian
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704018/
https://ncbi.nlm.nih.gov/pubmed/23776234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221803110
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