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Muscarinic acetylcholine receptor activation blocks long-term potentiation at cerebellar parallel fiber–Purkinje cell synapses via cannabinoid signaling
Muscarinic acetylcholine receptors (mAChRs) are known to modulate synaptic plasticity in various brain areas. A signaling pathway triggered by mAChR activation is the production and release of endocannabinoids that bind to type 1 cannabinoid receptors (CB1R) located on synaptic terminals. Using whol...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3704018/ https://ncbi.nlm.nih.gov/pubmed/23776234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221803110 |
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