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Age-changes in gene expression in primary mixed glia cultures from young vs old rat cerebral cortex are modified by interactions with neurons

Astrocytic GFAP expression increases during normal aging in many brain regions and in primary astrocyte cultures derived from aging rodent brains. As shown below, we unexpectedly found that the age-related increase of GFAP expression was suppressed in mixed glia (astrocytes + microglia). However, th...

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Main Authors: Kremsky, Isaac, Morgan, Todd E., Hou, Xiaogang, Li, Lei, Finch, Caleb E.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703782/
https://ncbi.nlm.nih.gov/pubmed/22226781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2011.12.008
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