Suppression of NZB/NZW murine nephritis by administration of a syngeneic monoclonal antibody to DNA. Possible role of anti-idiotypic antibodies.

Suppression of circulating antibodies to double-stranded DNA was achieved in NZB/NZW f1 female mice by repeated administration of an IgG2a monoclonal antibody to DNA. Deaths from nephritis were delayed; glomerular deposition of IgG and of the cationic IgG DNA antibodies characteristic of murine lupu...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Hahn, B H, Ebling, F M
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1983
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370377/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6223048/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110927
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