Interleukin 6 promotes murine lupus in NZB/NZW F1 mice.
To investigate the role of IL-6 in systemic lupus erythematosus (SLE), we selectively inhibited IL-6 in lupus-prone NZB/NZW F1(B/W) mice by chronic administration of a rat mAb to mouse IL-6. Anti-IL-6 alone elicited an anti-rat response that blocked its biologic effects. To circumvent this problem,...
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| Pubblicato in: | J Clin Invest |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
1994
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296134/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040314/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117373 |
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