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Inhibition of norovirus replication by morpholino oligomers targeting the 5′-end of the genome

Noroviruses are an important cause of non-bacterial epidemic gastroenteritis, but no specific antiviral therapies are available. We investigated the inhibitory effect of phosphorodiamidiate morpholino oligomers (PMOs) targeted against norovirus sequences. A panel of peptide-conjugated PMOs (PPMOs) s...

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Detalhes bibliográficos
Main Authors: Bok, Karin, Cavanaugh, Victoria J., Matson, David O., González-Molleda, Lorenzo, Chang, Kyeong-Ok, Zintz, Carmelann, Smith, Alvin W., Iversen, Patrick, Green, Kim Y., Campbell, Ann E.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703767/
https://ncbi.nlm.nih.gov/pubmed/18783811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.08.007
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