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RNase-L deficiency exacerbates experimental colitis and colitis-associated cancer
BACKGROUND: The endoribonuclease RNase-L is a type-I interferon (IFN)-regulatedcomponent of the innate immune response that functions in antiviral, antibacterial and antiproliferative activities. RNase-L produces RNA agonists of RIG-I-like receptors (RLRs), sensors of cytosolic pathogen-associated R...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3703736/ https://ncbi.nlm.nih.gov/pubmed/23567782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0b013e318281f2fd |
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