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Adenosine deaminase messenger RNAs in lymphoblast cell lines derived from leukemic patients and patients with hereditary adenosine deaminase deficiency.

Hereditary deficiency of adenosine deaminase (ADA) usually causes profound lymphopenia with severe combined immunodeficiency disease. Cells from patients with ADA deficiency contain less than normal, and sometimes undetectable, amounts of ADA catalytic activity and ADA protein. The molecular defects...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Adrian, G S, Hutton, J J
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1983
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370370/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6134754/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110920
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