Constitutive Proteasomal Degradation of TWIST-1 in Epithelial Ovarian Cancer Stem Cells Impacts Differentiation and Metastatic Potential

Epithelial-mesenchymal transition (EMT) is a critical process for embryogenesis but is abnormally activated during cancer metastasis and recurrence. This process enables epithelial cancer cells to acquire mobility and traits associated with stemness. It is unknown whether epithelial stem cells or ep...

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Autori principali: Yin, Gang, Alvero, Ayesha B., Craveiro, Vinicius, Holmberg, Jennie C., Fu, Han-Hsuan, Montagna, Michele K., Yang, Yang, Chefetz-Menaker, Ilana, Nuti, Sudhakar, Rossi, Michael, Silasi, Dan-Arin, Rutherford, Thomas, Mor, Gil
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703656/
https://ncbi.nlm.nih.gov/pubmed/22349827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.33
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