Inhibition of Aurora-A kinase induces cell cycle arrest in epithelial ovarian cancer stem cells by affecting NFκB pathway

Recurrent ovarian cancer is resistant to conventional chemotherapy. A sub-population of ovarian cancer cells, the epithelial ovarian cancer stem cells (EOC stem cells) have stemness properties, constitutive NFκB activity, and represent the chemoresistant population. Currently, there is no effective...

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Detalhes bibliográficos
Main Authors: Chefetz, Ilana, Holmberg, Jennie C, Alvero, Ayesha B, Visintin, Irene, Mor, Gil
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154367/
https://ncbi.nlm.nih.gov/pubmed/21623171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.13.16348
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