Unique Versus Redundant Functions of IL-1α and IL-1β in the Tumor Microenvironment

Interleukin-1 (IL-1) is a major “alarm” upstream pro-inflammatory cytokine that also affects immunity and hematopoiesis by inducing cytokine cascades. In the tumor arena, IL-1 is produced by malignant or microenvironmental cells. As a pleiotropic cytokine, IL-1 is involved in tumorigenesis and tumor...

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Autors principals: Voronov, Elena, Dotan, Shahar, Krelin, Yakov, Song, Xiaoping, Elkabets, Moshe, Carmi, Yaron, Rider, Peleg, Idan Cohen, Romzova, Marianna, Kaplanov, Irena, Apte, Ron N.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2013
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703603/
https://ncbi.nlm.nih.gov/pubmed/23847618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00177
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