Imaging changes in synaptic acetylcholine availability in living human subjects

INTRODUCTION: In vivo estimation of beta2-nicotinic acetylcholine receptor (β(2)*-nAChR) availability with molecular neuroimaging is complicated by competition between the endogenous neurotransmitter ACh and the radioligand [(123)I]5-IA-85380 ([(123)I]5-IA). We examined whether binding of [(123)I]5-...

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Detalhes bibliográficos
Main Authors: Esterlis, Irina, Hannestad, Jonas O., Bois, Frederic, Sewell, R. Andrew, Tyndale, Rachel, Seibyl, John P., Picciotto, Marina R., Laruelle, Marc, Carson, Richard E., Cosgrove, Kelly P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703589/
https://ncbi.nlm.nih.gov/pubmed/23160789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.112.111922
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