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Chromatin Effector Pygo2 Mediates Wnt-Notch Cross-talk to Suppress Luminal/Alveolar Potential of Mammary Stem and Basal Cells
Epigenetic mechanisms regulating lineage differentiation of mammary stem cells (MaSCs) remain poorly understood. Pygo2 is a histone methylation reader and a context-dependent Wnt/β-catenin co-activator. Here we provide evidence for Pygo2’s function in suppressing luminal/alveolar differentiation of...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3703489/ https://ncbi.nlm.nih.gov/pubmed/23684539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.04.012 |
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