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Chromatin effector Pygo2 regulates mammary tumor initiation and heterogeneity in MMTV-Wnt1 mice

Little is known about chromatin mechanisms that regulate tumor-initiating cells that are proposed to be responsible for tumor recurrence and relapse. We have previously shown that Pygopus 2 (Pygo2), a chromatin effector and context-dependent Wnt signaling co-activator, regulates mammary gland develo...

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Bibliografiska uppgifter
Huvudupphovsmän: Watanabe, Kazuhide, Fallahi, Magid, Dai, Xing
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913260/
https://ncbi.nlm.nih.gov/pubmed/23334328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.620
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