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Sarcomatoid lung carcinomas show high levels of Programmed death Ligand-1 (PD-L1)

Programmed death-1 (PD-1) is a co-inhibitory inducible receptor present on T-cells and macrophages. Tumor cells with increased programmed death ligand-1 (PD-L1) are believed to escape immunity through activation of PD-1/PD-L1 pathway and suppression of effector immune responses. Recent strategies ta...

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Autori principali: Velcheti, Vamsidhar, Rimm, David L., Schalper, Kurt A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703468/
https://ncbi.nlm.nih.gov/pubmed/23676558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e318292be18
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