High SOX2 Levels Predict Better Outcome in Non-Small Cell Lung Carcinomas

BACKGROUND: SOX2 is an embryonic developmental transcription factor, which is important in the development of the respiratory tract. SOX2 overexpression is associated with aggressive disease in several tumor types. However, SOX2 overexpression and gene amplification associates with favorable outcome...

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Main Authors: Velcheti, Vamsidhar, Schalper, Kurt, Yao, Xiaopan, Cheng, Huan, Kocoglu, Mehmet, Dhodapkar, Kavita, Deng, Yanhong, Gettinger, Scott, Rimm, David L.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631238/
https://ncbi.nlm.nih.gov/pubmed/23620753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061427
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