Arteriogenic therapy based on simultaneous delivery of VEGF-A and FGF4 genes improves the recovery from acute limb ischemia

BACKGROUND: Gene therapy stimulating the growth of blood vessels is considered for the treatment of peripheral and myocardial ischemia. Here we aimed to achieve angiogenic synergism between vascular endothelial growth factor-A (VEGF-A, VEGF) and fibroblast growth factor 4 (FGF4) in murine normoperfu...

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Hauptverfasser: Jazwa, Agnieszka, Tomczyk, Mateusz, Taha, Hevidar M, Hytonen, Elisa, Stoszko, Mateusz, Zentilin, Lorena, Giacca, Mauro, Yla-Herttuala, Seppo, Emanueli, Costanza, Jozkowicz, Alicja, Dulak, Jozef
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703285/
https://ncbi.nlm.nih.gov/pubmed/23816205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-824X-5-13
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