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Molecular Defect of Spectrin in Hereditary Pyropoikilocytosis: ALTERATIONS IN THE TRYPSIN-RESISTANT DOMAIN INVOLVED IN SPECTRIN SELF-ASSOCIATION

In hereditary pyropoikilocytosis (HPP) the erythrocyte membrane skeleton exhibits mechanical instability that can be correlated to defective self-association of spectrin heterodimers. To detect structural changes in the functional domains of HPP spectrin we have examined the peptide pattern produced...

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Bibliografische gegevens
Hoofdauteurs: Lawler, Jack, Liu, Shih-Chun, Palek, Jiri, Prchal, Josef
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1982
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC370314/
https://ncbi.nlm.nih.gov/pubmed/7130392
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