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Molecular Defect of Spectrin in Hereditary Pyropoikilocytosis: ALTERATIONS IN THE TRYPSIN-RESISTANT DOMAIN INVOLVED IN SPECTRIN SELF-ASSOCIATION
In hereditary pyropoikilocytosis (HPP) the erythrocyte membrane skeleton exhibits mechanical instability that can be correlated to defective self-association of spectrin heterodimers. To detect structural changes in the functional domains of HPP spectrin we have examined the peptide pattern produced...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1982
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC370314/ https://ncbi.nlm.nih.gov/pubmed/7130392 |
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