Tocilizumab infusion therapy normalizes inflammation in sporadic ALS patients

Patients with sporadic amyotrophic lateral sclerosis (sALS) show inflammation in the spinal cord and peripheral blood. The inflammation is driven by stimulation of macrophages by aggregated superoxide dismutase 1 (SOD1) through caspase1, interleukin 1 (IL1), IL6 and chemokine signaling. Inflammatory...

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Detaylı Bibliyografya
Asıl Yazarlar: Fiala, Milan, Mizwicki, Mathew T, Weitzman, Rachel, Magpantay, Larry, Nishimoto, Norihiro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: e-Century Publishing Corporation 2013
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703125/
https://ncbi.nlm.nih.gov/pubmed/23844337
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