Prolonged Exposure to HIV Reinforces a Poised Epigenetic Program for PD-1 Expression in Virus-specific CD8 T Cells

Antigen-specific CD8 T cells play a critical role in controlling HIV infection but eventually lose antiviral functions in part because of expression and signaling through the inhibitory PD-1 receptor. To better understand the impact of prolonged TCR ligation on regulation of PD-1 expression in HIV-s...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Youngblood, Ben, Noto, Alessandra, Porichis, Filippos, Akondy, Rama S., Ndhlovu, Zaza M., Austin, James W., Bordi, Rebeka, Procopio, Francesco A., Miura, Toshiyuki, Allen, Todd M., Sidney, John, Sette, Alessandro, Walker, Bruce D., Ahmed, Rafi, Boss, Jeremy M., Sékaly, Rafick-Pierre, Kaufmann, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702641/
https://ncbi.nlm.nih.gov/pubmed/23772031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203161
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados