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Meprin A and meprin α generate biologically functional IL-1β from pro-IL-1β
The present study demonstrates that the oligomeric metalloendopeptidase meprin A purified from kidney cortex and recombinant meprin α are capable of generating biologically active IL-1β from its precursor pro-IL-1β. Amino-acid sequencing analysis reveals that meprin A and meprin α cleave pro-IL-1β a...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3702385/ https://ncbi.nlm.nih.gov/pubmed/19135030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.12.161 |
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