Meprin A and meprin α generate biologically functional IL-1β from pro-IL-1β

The present study demonstrates that the oligomeric metalloendopeptidase meprin A purified from kidney cortex and recombinant meprin α are capable of generating biologically active IL-1β from its precursor pro-IL-1β. Amino-acid sequencing analysis reveals that meprin A and meprin α cleave pro-IL-1β a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Herzog, Christian, Haun, Randy S., Kaushal, Varsha, Mayeux, Philip, Shah, Sudhir V., Kaushal, Gur P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702385/
https://ncbi.nlm.nih.gov/pubmed/19135030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.12.161
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