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Pleiotropic actions of miR-21 highlight the critical role of deregulated stromal microRNAs during colorectal cancer progression

The oncogene microRNA-21 (miRNA; miR-21) is overexpressed in most solid organ tumours; however, a recent examination of stage II colorectal cancer (CRC) specimens suggests this may be a stromal phenomenon and not only a feature of cancer cells. In vitro and in vivo studies show that miR-21 has poten...

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Detalhes bibliográficos
Main Authors: Bullock, M D, Pickard, K M, Nielsen, B S, Sayan, A E, Jenei, V, Mellone, M, Mitter, R, Primrose, J N, Thomas, G J, Packham, G K, Mirenzami, A H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702298/
https://ncbi.nlm.nih.gov/pubmed/23788041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.213
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