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The embryonic transcription factor Brachyury blocks cell cycle progression and mediates tumor resistance to conventional antitumor therapies

The T-box transcription factor Brachyury, a molecule frequently detected in human cancers but seldom found in normal adult tissue, has recently been characterized as a driver of the epithelial-to-mesenchymal switch of human carcinomas. In the current investigation, we present data demonstrating that...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Huang, B, Cohen, J R, Fernando, R I, Hamilton, D H, Litzinger, M T, Hodge, J W, Palena, C
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702290/
https://ncbi.nlm.nih.gov/pubmed/23788039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.208
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