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miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer

Resistance to fluoropyrimidine-based chemotherapy is the major reason for the failure of advanced colorectal cancer (CRC) treatment. The lack of ability of tumor cells to undergo apoptosis after genotoxic stress is the key contributor to this intrinsic mechanism. Mounting evidence has demonstrated t...

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Detalhes bibliográficos
Main Authors: Karaayvaz, M, Zhai, H, Ju, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702282/
https://ncbi.nlm.nih.gov/pubmed/23744359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.193
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