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NFAT5 represses canonical Wnt signaling via inhibition of β-catenin acetylation and participates in regulating intestinal cell differentiation

The intestinal mucosa undergoes a continual process of proliferation, differentiation, and apoptosis, which is regulated by multiple signaling pathways. The Wnt/β-catenin pathway has a critical role in this process. Previously, we have shown that the calcineurin-dependent nuclear factor of activated...

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Detalhes bibliográficos
Main Authors: Wang, Q, Zhou, Y, Rychahou, P, Liu, C, Weiss, H L, Evers, B M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702276/
https://ncbi.nlm.nih.gov/pubmed/23764852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.202
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