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Intraductal Delivery of Adenoviruses Targets Pancreatic Tumors in Transgenic Ela-myc Mice and Orthotopic Xenografts

Gene-based anticancer therapies delivered by adenoviruses are limited by the poor viral distribution into the tumor. In the current work we have explored the feasibility of targeting pancreatic tumors through a loco-regional route. We have taken advantage of the ductal network in the pancreas to ret...

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Hlavní autoři: José, Anabel, Sobrevals, Luciano, Camacho-Sánchez, Juan Miguel, Huch, Meritxell, Andreu, Núria, Ayuso, Eduard, Navarro, Pilar, Alemany, Ramon, Fillat, Cristina
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702210/
https://ncbi.nlm.nih.gov/pubmed/23328228
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