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DNA Catalysis of a Normally Disfavored RNA Hydrolysis Reaction
We recently used in vitro selection to identify many deoxyribozymes that catalyze DNA phosphodiester bond hydrolysis and create 5′-phosphate and 3′-hydroxyl termini. Alternatively, numerous deoxyribozymes have been identified for catalysis of RNA cleavage by 2′-hydroxyl transesterification, forming...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3702039/ https://ncbi.nlm.nih.gov/pubmed/23697866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4032488 |
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