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Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression

The tumor microenvironment is a complex milieu of tumor and host cells. Host cells can include tumor-reactive T cells capable of killing tumor cells. However, more frequently the tumor and host components interact to generate a highly immune suppressive environment that frustrates T cell cytotoxicit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ostrand-Rosenberg, Suzanne, Sinha, Pratima, Beury, Daniel W., Clements, Virginia K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701942/
https://ncbi.nlm.nih.gov/pubmed/22313874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2012.01.011
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