The Interferon-Signature of Sjögren’s Syndrome: How Unique Biomarkers Can Identify Underlying Inflammatory and Immunopathological Mechanisms of Specific Diseases

Innate immune responses direct the nature and specificity of downstream adaptive responses in autoimmune diseases. One of the strongest markers of innate immunity is the up-regulated expression of interferon (IFN) and IFN-responsive/stimulated genes (IRGs/ISGs). While multiple IRGs are induced durin...

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Bibliographic Details
Main Authors: Nguyen, Cuong Quoc, Peck, Ammon Broughton
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2013
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701867/
https://ncbi.nlm.nih.gov/pubmed/23847613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00142
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