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The Interferon-Signature of Sjögren’s Syndrome: How Unique Biomarkers Can Identify Underlying Inflammatory and Immunopathological Mechanisms of Specific Diseases

Innate immune responses direct the nature and specificity of downstream adaptive responses in autoimmune diseases. One of the strongest markers of innate immunity is the up-regulated expression of interferon (IFN) and IFN-responsive/stimulated genes (IRGs/ISGs). While multiple IRGs are induced durin...

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Detalhes bibliográficos
Main Authors: Nguyen, Cuong Quoc, Peck, Ammon Broughton
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701867/
https://ncbi.nlm.nih.gov/pubmed/23847613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00142
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