Evidence for Two Tissue-specific Pathways for In Vivo Thyroxine 5′-Deiodination in the Rat

Propylthiouracil (PTU) is a well known inhibitor of thyroxine (T(4)) to triiodothyronine (T(3)) conversion as evidenced by its effect in several in vitro systems and by the decrease in serum T(3) caused by this drug in either rats or man receiving T(4) replacement. However, the failure of PTU to dec...

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Bibliographic Details

Published in:	J Clin Invest
Main Authors:	Silva, J. Enrique, Leonard, Jack L., Crantz, Frank R., Larsen, P. Reed
Format:	Artigo
Language:	Inglês
Published:	American Society for Clinical Investigation 1982
Subjects:	Articles
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370183/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7068853/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110554
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