Instability of beta E-messenger RNA during erythroid cell maturation in hemoglobin E homozygotes.
Hemoglobin E interacts with beta-thalassemia to produce a disorder of variable severity that is the most common form of symptomatic thalassemia in Southeast Asia. The beta E-globin gene acts as a mild thalassemia gene; there are low levels of beta E-messenger RNA (mRNA) in reticulocytes, and prelimi...
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| Published in: | J Clin Invest |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
1982
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370162/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7076845/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110510 |
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