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Instability of beta E-messenger RNA during erythroid cell maturation in hemoglobin E homozygotes.

Hemoglobin E interacts with beta-thalassemia to produce a disorder of variable severity that is the most common form of symptomatic thalassemia in Southeast Asia. The beta E-globin gene acts as a mild thalassemia gene; there are low levels of beta E-messenger RNA (mRNA) in reticulocytes, and prelimi...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Traeger, J, Winichagoon, P, Wood, W G
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1982
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370162/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7076845/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110510
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