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Decreased Globin Messenger RNA in Thalassemia Detected by Molecular Hybridization

In previous studies of patients with β thalassemia, mRNA extracted from reticulocytes in peripheral blood when added to cell-free systems reproduces the deficient β-chain synthesis characteristic of intact cells. The present studies with specific probes for α and β mRNA were designed to decide wheth...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kacian, D. L., Gambino, R., Dow, L. W., Grossbard, E., Natta, C., Ramirez, F., Spiegelman, S., Marks, P. A., Bank, A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1973
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433619/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4124307/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.6.1886
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