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LKB1 Inhibits Breast Cancer Partially through Repressing the Hedgehog Signaling Pathway

Constitutive activation of the Hedgehog (Hh) signaling pathway has been implicated in the development of many human malignancies. Hh targets, such as Patched (PTCH), smoothened (SMO), Sonic hedgehog (SHH) and glioma-associated oncogene homologue 1 (GLI1), are markers of Hh signaling activation and e...

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Detalhes bibliográficos
Main Authors: Zhuang, Zhigang, Wang, Kai, Cheng, Xiaolin, Qu, Xueying, Jiang, Beiqi, Li, Zhengdong, Luo, Jianming, Shao, Zhiming, Duan, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701543/
https://ncbi.nlm.nih.gov/pubmed/23861764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067431
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