LKB1 Inhibits Breast Cancer Partially through Repressing the Hedgehog Signaling Pathway

Constitutive activation of the Hedgehog (Hh) signaling pathway has been implicated in the development of many human malignancies. Hh targets, such as Patched (PTCH), smoothened (SMO), Sonic hedgehog (SHH) and glioma-associated oncogene homologue 1 (GLI1), are markers of Hh signaling activation and e...

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Bibliografske podrobnosti
Main Authors: Zhuang, Zhigang, Wang, Kai, Cheng, Xiaolin, Qu, Xueying, Jiang, Beiqi, Li, Zhengdong, Luo, Jianming, Shao, Zhiming, Duan, Tao
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701543/
https://ncbi.nlm.nih.gov/pubmed/23861764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067431
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