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Mild and efficient cyanuric chloride catalyzed Pictet–Spengler reaction

A practical, mild and efficient protocol for the Pictet–Spengler reaction catalyzed by cyanuric chloride (trichloro-1,3,5-triazine, TCT) is described. The 6-endo cyclization of tryptophan/tryptamine and modified Pictet–Spengler substrates with both electron-withdrawing and electron-donating aldehyde...

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Autors principals: Sharma, Ashish, Singh, Mrityunjay, Rai, Nitya Nand, Sawant, Devesh
Format: Artigo
Idioma:Inglês
Publicat: Beilstein-Institut 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701375/
https://ncbi.nlm.nih.gov/pubmed/23843919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.140
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