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Strictosidine Synthase: Mechanism of a Pictet–Spengler Catalyzing Enzyme

The Pictet–Spengler reaction, which yields either a β-carboline or a tetrahydroquinoline product from an aromatic amine and an aldehyde, is widely utilized in plant alkaloid biosynthesis. Here we deconvolute the role that the biosynthetic enzyme strictosidine synthase plays in catalyzing the stereos...

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Bibliografiske detaljer
Main Authors: Maresh, Justin J., Giddings, Lesley-Ann, Friedrich, Anne, Loris, Elke A., Panjikar, Santosh, Trout, Bernhardt L., Stöckigt, Joachim, Peters, Baron, O’Connor, Sarah E.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079323/
https://ncbi.nlm.nih.gov/pubmed/18081287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja077190z
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