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The impact of orbitofrontal dysfunction on cocaine addiction

Cocaine addiction is characterized by poor judgment and maladaptive decision-making. Here we review evidence implicating the orbitofrontal cortex in such behavior. This evidence suggests that cocaine-induced changes in orbitofrontal cortex disrupt the representation of states and transition function...

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Detalhes bibliográficos
Main Authors: Lucantonio, Federica, Stalnaker, Thomas A, Shaham, Yavin, Niv, Yael, Schoenbaum, Geoffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701259/
https://ncbi.nlm.nih.gov/pubmed/22267164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3014
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