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Genome editing of human pluripotent stem cells to generate human cellular disease models

Disease modeling with human pluripotent stem cells has come into the public spotlight with the awarding of the Nobel Prize in Physiology or Medicine for 2012 to Drs John Gurdon and Shinya Yamanaka for the discovery that mature cells can be reprogrammed to become pluripotent. This discovery has opene...

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Autor principal: Musunuru, Kiran
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Limited 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701209/
https://ncbi.nlm.nih.gov/pubmed/23751357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.012054
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