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Curcumin alleviates immune-complex-mediated glomerulonephritis in factor-H-deficient mice

Complement factor H (Cfh) is a key regulator of the complement cascade and protects C57BL/6 mice from immune complex-mediated complement-dependent glomerulonephritis. In chronic serum sickness (CSS) there are increased deposits of immune complexes in the glomeruli with inflammation and a scarring ph...

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Hlavní autoři: Jacob, Alexander, Chaves, Lee, Eadon, Michael T, Chang, Anthony, Quigg, Richard J, Alexander, Jessy J
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701179/
https://ncbi.nlm.nih.gov/pubmed/23347386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12079
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