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CD8(+) CD122(+) regulatory T cells contain clonally expanded cells with identical CDR3 sequences of the T-cell receptor β-chain
We identified CD8(+) CD122(+) regulatory T cells (CD8(+) CD122(+) Treg cells) and reported their importance in maintaining immune homeostasis. The absence of CD8(+) CD122(+) Treg cells has been shown to lead to severe systemic autoimmunity in several mouse models, including inflammatory bowel diseas...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3701177/ https://ncbi.nlm.nih.gov/pubmed/23317140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12067 |
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