Methylation of the Claudin 1 Promoter Is Associated with Loss of Expression in Estrogen Receptor Positive Breast Cancer

Downregulation of the tight junction protein claudin 1 is a frequent event in breast cancer and is associated with recurrence, metastasis, and reduced survival, suggesting a tumor suppressor role for this protein. Tumor suppressor genes are often epigenetically silenced in cancer. Downregulation of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Di Cello, Francescopaolo, Cope, Leslie, Li, Huili, Jeschke, Jana, Wang, Wei, Baylin, Stephen B., Zahnow, Cynthia A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701071/
https://ncbi.nlm.nih.gov/pubmed/23844228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068630
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