Systemic Inhibition of Canonical Notch Signaling Results in Sustained Callus Inflammation and Alters Multiple Phases of Fracture Healing

The Notch signaling pathway is an important regulator of embryological bone development, and many aspects of development are recapitulated during bone repair. We have previously reported that Notch signaling components are upregulated during bone fracture healing. However, the significance of the No...

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Bibliographic Details
Main Authors: Dishowitz, Michael I., Mutyaba, Patricia L., Takacs, Joel D., Barr, Andrew M., Engiles, Julie B., Ahn, Jaimo, Hankenson, Kurt D.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701065/
https://ncbi.nlm.nih.gov/pubmed/23844237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068726
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