TLR-2/TLR-4 TREM-1 Signaling Pathway Is Dispensable in Inflammatory Myeloid Cells during Sterile Kidney Injury

Inflammatory macrophages are abundant in kidney disease, stimulating repair, or driving chronic inflammation and fibrosis. Damage associated molecules (DAMPs), released from injured cells engage pattern recognition receptors (PRRs) on macrophages, contributing to activation. Understanding mechanisms...

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Autors principals: Campanholle, Gabriela, Mittelsteadt, Kristen, Nakagawa, Shunsaku, Kobayashi, Akio, Lin, Shuei-Liong, Gharib, Sina A., Heinecke, Jay W., Hamerman, Jessica A., Altemeier, William A., Duffield, Jeremy S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700949/
https://ncbi.nlm.nih.gov/pubmed/23844229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068640
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