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Sulphatation Does Not Appear to Be a Protective Mechanism to Prevent Oxysterol Accumulation in Humans and Mice

24S- and 27-hydroxycholesterol (24OHC and 27OHC) are potent regulators of different biochemical systems in vitro and are the major circulating oxysterols. A small fraction of these oxysterols has been reported to be sulphated but there are no detailed studies. We considered the possibility that sulp...

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Detalhes bibliográficos
Main Authors: Acimovic, Jure, Lövgren-Sandblom, Anita, Olin, Maria, Ali, Zeina, Heverin, Maura, Schüle, Rebecca, Schöls, Ludger, Fischler, Björn, Fickert, Peter, Trauner, Michael, Björkhem, Ingemar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700920/
https://ncbi.nlm.nih.gov/pubmed/23844150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068031
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