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Ambushing the ambush hypothesis: predicting and evaluating off-frame codon frequencies in Prokaryotic Genomes

BACKGROUND: In this paper, we address the evidence for the Ambush Hypothesis. Proposed by Seligmann and Pollock, this hypothesis posits that there exists a selection for off-frame stop codons (OSCs) to counteract the possible deleterious effects of translational frameshifts, including the waste of r...

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Detalhes bibliográficos
Main Authors: Morgens, David W, Chang, Charlotte H, Cavalcanti, Andre RO
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700767/
https://ncbi.nlm.nih.gov/pubmed/23799949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-418
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